CHE 105. The Environment and its Chemistry: Laboratory (1 Cr.) (GEN. ED. #6 with CHE 106) (LER-NS WITH CHE 106)
Laboratory experiments that illustrate topics covered in CHE 106. Not open to students who have completed CHE 112. Prerequisite or co-requisite: CHE 106. Three hours lab Spring semester. Offered 2014-15 and alternate years. Amann.

CHE 106. The Environment and its Chemistry (3 Cr.) (GEN. ED. #11; GEN. ED. #6 with CHE 105) (LER-ENV; AND NS WITH CHE 105)
Introduction to chemistry with special emphasis on environmental issues important to our communities, such as water and air quality, natural resource availability and energy production from renewable resources, fossil fuels, and nuclear plants. Environmental topics such as green chemistry and remediation techniques will be studied. Three hours lecture. Not open to students who have completed CHE 111. Spring semester. Amann.

CHE 111. Principles of Chemistry I (3 Cr.) (GEN. ED. #6 with CHE 112 OR CHE 112H) (LER–NS WITH CHE 112)
Structure and properties of atoms and molecules and the states of matter, relationship of electronic structure to the properties of elements and simple compounds, properties of solutions, acid-base and redox reactions in solution. Prerequisite: A score of M on the mathematics placement exam. Corequisite: CHE 112 (or CHE 112H). Three hours lecture and 90-minute workshop. Fall semester. Douglass.

CHE 112. Principles of Chemistry I: Laboratory (1 Cr.) (GEN. ED. #6 with CHE 111) (LER-NS WITH CHE 111)
Experiments that illustrate topics covered in CHE 111. Corequisite: CHE 111. Three hours lab. Fall semester. Amann, Levine.

CHE 112H. Chemical Principles: Honors Laboratory (2 Cr.) (GEN. ED. #6 with CHE 111)
Synthesis of compounds followed by experiments to elucidate their chemical structure and behavior. Development of laboratory techniques and experience with modern instrumental methods. One hour lecture, three hours laboratory. Placement by department only. Corequisite: CHE 111 or AP credit. Fall semester. Schultz.

CHE 151. Principles of Chemistry II: Lecture (3 Cr.) 
The theory of chemical kinetics, thermodynamics, electrochemistry, aspects of solution equilibria, including solubility, acid-base reactions, redox reactions, and complex formation. Prerequisites: CHE 111 and CHE 112 (or CHE 112H) or permission of the instructor. Corequisite: CHE 152 (or CHE 152H). Three hours lecture and 90-minute workshop. Spring semester. Gibbs.

CHE 152. Principles of Chemistry II: Laboratory (1 Cr.) 
A laboratory experience demonstrating the principles and applications of the theories discussed in CHE 151. Three hours laboratory Prerequisites: CHE 111 and CHE 112 (or CHE 112H). Corequisite: CHE 151. Spring semester. Douglass, Levine.

CHE 152H. Principles of Chemistry II: Honors Laboratory (2 Cr.) 
Continuation of experiments in CHE 112H, including those that illustrate the topics covered in CHE 151. A multi-week independent project is also completed. One hour lecture, three hours laboratory. Placement by department only. Corequisite: CHE 151 or permission of the instructor. Spring semester. Douglass.

CHE 230. Organic Chemistry I (4 Cr.) 
Chemistry of the compounds of carbon with emphasis on the relation of molecular structure to chemical and physical behavior. Topics covered include functional groups, nomenclature, structure, bonding, isomers, confromations, chirality, reactions that proceed through ionic mechanisms, structure elucidation using NMR, MS, and IR, and introduction to multistep synthesis. Specific reactions covered include acid-base, nucleophilic substitution, elimination, oxidation, reduction, and carbon-carbon bond formation reactions. Laboratory work includes appropriate techniques, synthetic and analytical methods including melting points, recrystallization, distllation, chroatography, extraction, GC/MS, and IR.  Three hours lecture, three hours laboratory. Prerequisites: CHE 151 and CHE 152 (or CHE 152H) with grades of C- or better. Fall semester. Ahmed-Schofield, Greco, Schultz .

CHE 235. Organic Chemistry II (4 Cr.) 
Continuation of CHE 230. Topics covered include chemistry of carbonyl groups, amines, alkenes, and aromatic rings, as well as reactions proceeding through pericyclic and radical mechanisms.  Lab work includes hands-on use of the NMR spectrometer along with instrumentation introduced in CHE 230. Three hours lecture, three hours laboratory. Prerequisite: CHE 230 with a grade of C- or better. Spring semester. Ahmed-Schofield.

CHE 240. Biophysical Chemistry (3 Cr.) 
Exploration of the states of matter and laws of thermodynamics applied to chemical systems, and rates of reactions. Emphasis will be placed on the physical chemistry of biological systems and the theoretical basis for various biophysical techniques. Prerequisites: MA 180 and PHY 115 or 125, CHE 151 and CHE 152 (or 152H). Recommended BIO 210. Spring semester. Sibley.

CHE 245. Chemical Information Literacy (1 Cr.) 
Introduction to the chemical literature. Students will learn about the different kinds of journals and databases that contain reliable chemical information, how to search for information, and how to organize that information. Topics covered will span the breadth of modern chemistry. Prerequisite: CHE 230. Spring Semester. First offered 2015. Greco.

CHE 265. Physical Chemistry: Quantum & Spectroscopy (3 Cr.) 
Introduction to quantum theory and its applications to chemistry and atomic and molecular spectroscopy. Three hours lecture. Prerequisites: CHE 240 or department permission, MA 180, PHY 116 or 126.CHE 240 Fall semester. Douglass.

CHE 265L. Physical Chemistry Lab (2 Cr.) 
Laboratory for topics covered in CHE 240 and  CHE 265. Experiments will focus on spectroscopy, molecular structure, rates of reactions, and laws of thermodynamics. Pre- or corequisite: CHE 265. One hour lecture, three hours laboratory. Fall semester. Sibley.

CHE 270. Environmental and Green Chemistry (3 Cr.) (GEN. ED. #11) (LER–ENV)
Exploration of the chemistry of the environment including the atmosphere, soil, water, and energy sources. Emphasis will be placed on perturbations of natural processes as a result of human activity and on the principles of green chemistry, through which chemists could reduce their footprint on the environment. Three hour lecture. Pre- or co-requisite CHE 230. Fall Semester. Offered 2014-15 and alternate years. Schultz.

CHE 290. Internship in Chemistry (3-4 Cr.) 
Internships in research laboratories in universities and industry. Arranged on the basis of the individual interest of the student. Prerequisite: junior or senior chemistry major. Preliminary interview required. Graded pass/no pass only.Department.

CHE 294. Independent Work in Chemistry (2-3 Cr.) (GEN. ED. #6 and #7)
Independent laboratory project and associated library work carried out under the supervision of a department member. Prerequisite: junior standing as a chemistry major, minimum GPA of 3.0 in chemistry courses and permission of the instructor. Fall semester, repeated spring semester. Department.

CHE 295. Directed Reading in Chemistry (3 Cr.) (GEN. ED. #7)
Directed reading in a field for which the student has the required background. A formal written report is required. One semester. Prerequisites: junior or senior standing as a chemistry major and permission of the instructor. Fall semester, repeated spring semester.Department.

CHE 330. Organic Chemistry III (3 Cr.) (GEN. ED. #7)
Exploration of strategy and tactics in organic synthesis.  In depth study of reactions that form C-C bonds, functional group interconversions, and pericyclic reactions.  Reaction stereochemistry and use in multistep synthesis will be emphasized.  Students will independently investigate the synthesis of a molecule of their choice and present their findings to the class. Three hours lecture. Prerequisite: CHE 235. Fall semester. Offered 2015-2016 and alternate years. Schultz.

CHE 335. Chemical Communication (1 Cr.) 
In-depth investigation of a topic of student's choice culminating in writing a review article and giving an oral presentation. Prerequisite: CHE 245. Spring Semester. First offered 2016. Department.

CHE 341. Biochemistry I (3 Cr.) 
Structure and function of biological molecules, chemistry of enzyme-catalyzed reactions, intermediary metabolism. Three hours lecture. Prerequisites: CHE 235 and one college-level general biology course, or permission of the instructor. Note that this course may only be counted toward a single major or minor. Spring semester. Levine.

CHE 342. Techniques in Biochemistry (2 Cr.) 
Introduction to the basic techniques for studying the structure and function of biological molecules. Emphasis is on protein purification and enzyme activity assays. One hour lecture, three hours laboratory. Pre- or corequisite: CHE 341. Note that this course may only be counted toward a single major or minor. Spring semester. Amann, Levine.

CHE 345. Biochemistry of Gene Expression (3 Cr.) 
Chemical and physical properties of nucleic acids; mechanisms of DNA replication, recombination, and repair; biochemistry of transcription, processing, and translation of genetic information. Emphasis on experimental basis for current knowledge and ongoing areas of research. Three hours lecture. Prerequisite: CHE 341 or the combination of CHE 235 and BIO 220 or permission of the instructor. Note that this course may only be counted toward a single major or minor. Fall semester. Offered 2014-2015 and alternating years. Levine.

CHE 346. Techniques in Biochemistry II: Laboratory (2 Cr.) 
Techniques in purification and physical and chemical analysis of nucleic acids. One hour lecture, three hours laboratory. Pre- or corequisite: CHE 345. Note that this course may only be counted toward a single major or minor. Fall semester. Not offered 2014-15. Levine.

CHE 355. Modern Methods of Chemical Analysis (3 Cr.) 
Powerful methods have developed in recent years for analyzing and separating mixtures and for determining molecular structure. A survey of these methods with emphasis on the design, application, and basic chemical principles involved in using these techniques. Comparison of methods with regard to type of data obtainable, sensitivity, selectivity, and cost. Three hours lecture. Pre- or corequisites: CHE 230. Fall semester. Sibley.

CHE 356. Modern Methods of Chemical Analysis Laboratory (2 Cr.) 
Experience with a variety of chemical and instrumental methods (as covered in CHE 355) for analyzing the structure and composition of materials. Exposure to techniques within the areas of chromatography, spectroscopy, and electrochemistry. Course includes a multi-week independent project. One hour lecture, three hours laboratory. Prerequisite: CHE 230. Fall semester. Greco.

CHE 372. Inorganic Chemistry (3 Cr.) 
Structure, bonding, and reactivity of coordination and organometallic compounds. Course has a strong emphasis on group theory and molecular theory. Three hours lecture. Prerequisites: CHE 230. Spring semester. Offered 2014-15 and alternate years. Greco.

CHE 373. Inorganic Chemistry Laboratory (2 Cr.) 
Synthesis, purification, and characterization of metal-containing compounds including compounds that are catalysts for organic reactions. One hour lecture, three hours laboratory. Prerequisites: CHE 235. Corequisite: CHE 372. Spring semester. Offered 2014-15 and alternate years. Greco.

CHE 380. Medicinal Chemistry (3 Cr.) 
An interdisciplinary capstone course about the chemistry of drugs. Topics include therapeutic targets of pharmaceuticals, the drug discovery process including quantitative structure-activity relationships, the fate of a drug in the body from administration to removal, and the detailed mechanism of action of selected drugs. Prerequisites: CHE 235 and either BIO 210 or CHE 341. Spring semester. Offered 2015-2016 and alternate years. Greco.

CHE 391H. Advanced Topics in Chemistry, Honors (2-3 Cr.) 
Seminar courses are offered to extend knowledge in an area of chemistry of student interest through assigned readings from the current literature, problem sets, and/or requiring considerable student independence. Topics are determined by student interest and needs. Sample topics include: Introduction to Materials Science (Sibley), Light and Life (Douglass), and Nuclear Magnetic Resonance (Greco). Oral presentation(s) and, in some cases, a formal written report are required. CHE 391H is a full-semester course. Prerequisites: CHE 235 and permission of the department; additional courses as appropriate for the particular seminar topic will be specified by the department.

CHE 392H. Advanced Topics in Chemistry, Honors (1.5 Cr.) 
See description in CHE 391H. CHE 392H is the first seven weeks. CHE 393H is the second seven weeks. Prerequisites: CHE 235 and permission of the department; additional courses as appropriate for the topic will be specified by the department. Fall semester, repeated spring semester. Department.

CHE 393H. Advanced Topics in Chemistry, Honors (1.5 Cr.) 
See description in CHE 391H. CHE 392H is the first seven weeks. CHE 393H is the second seven weeks. Prerequisites: CHE 235 and permission of the department; additional courses as appropriate for the topic will be specified by the department. Fall semester, repeated spring semester. Department.

CHE 395Y. Independent Work in Chemistry (2-4 Cr.) (GEN. ED. #6 and #7)
Independent laboratory project and associated library work carried out under the supervision of a member of the department. A formal written report, electronic portfolio, and presentation of research findings in a departmental seminar and attendance at designated campus events and seminars are required. May be repeated. A minimum of 4 credits of CHE 395Y, ordinarily spread over two semesters, is required for the ACS-certified degree. Prerequisites: senior standing as a chemistry major, minimum GPA of 3.0 in chemistry courses and permission of the department. Fall semester, repeated spring semester. Department.